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New Skin Treatment:

Plenhyage XL

Biological effects of PDRN (Polydeoxyribonucleotide):

  1. Stimulate cell proliferation

  2. Regenerative

  3. Synthesis of collagen and elastin

  4. Synthesis of Hyaluronic Acid

  5. Induces Angiogenesis

  6. Melanogenesis Inhibition

  7. Anti Inflammatory Effect

  8. Restore Fibroblast Biosynthetic Activity


Research and clinical evidence

Research studies have shown the following effects:

  • 115% increase in skin hydration

  • Over 50% increase in skin thickness

  • 47% increase in collagen production

  • 38% increase in skin elasticity

  • Reduction in inflammatory redness and improvement in rosacea and acne

  • Improvement in acne scarring

  • Reduction in pigmentation resulting from sun exposure

Plenhyage XL polynucleotide-based gel injectable has emerged as a revolutionary treatment option. This groundbreaking injectable harnesses the power of polynucleotides, biologically active molecules derived from DNA and RNA, to stimulate the skin's natural regenerative processes. Supported by evidence-based research, Plenhyage XL injectable offers a transformative solution for those seeking effective and long-lasting skin rejuvenation.

This treatment addresses various signs of ageing, such as fine lines, wrinkles, loss of skin elasticity and hydration, acne scarring, hyperpigmentation and rosacea. The injectable gel contains polynucleotides, which are short chains of nucleotides that play critical roles in cellular repair and regeneration. When introduced into the skin through precise injections, polynucleotides activate fibroblasts and stimulate collagen production, promoting tissue repair, and rejuvenating the complexion with firmer and more hydrated looking skin.

Evidence-Based Benefits of Plenhyage XL Polynucleotide-Based Gel Injectable:

  1. Collagen Synthesis and Improved Skin Elasticity: A study published in the Journal of Cosmetic Dermatology demonstrated that Plenhyage XL polynucleotide-based gel injectable significantly increased collagen synthesis in the skin. This boost in collagen production enhances skin elasticity and firmness, leading to a reduction in the appearance of fine lines and wrinkles.

  2. Enhanced Skin Hydration and Moisture Retention: Plenhyage XL injectable has been shown to improve skin hydration levels. A clinical trial published in the Journal of Clinical and Aesthetic Dermatology reported that participants experienced increased skin moisture content after receiving the treatment, resulting in a more supple and hydrated complexion.

  3. Reduction of Fine Lines and Wrinkles: In the same study mentioned above, patients who received Plenhyage XL polynucleotide-based gel injectable reported visible reduction in fine lines and wrinkles. The treatment targets these common signs of aging, leading to smoother and more youthful-looking skin.

  4. Tissue Repair and Regeneration: Plenhyage XL injectable's regenerative properties have been investigated in studies focused on wound healing and tissue repair. The polynucleotides in the gel stimulate cell growth and tissue regeneration, making it an ideal treatment for improving the overall health and appearance of the skin.

  5. Non-Invasive with Minimal Downtime: Plenhyage XL polynucleotide-based gel injectable is a minimally invasive treatment compared to surgical procedures. As a result, the procedure typically involves minimal downtime, allowing patients to resume their daily activities shortly after the injections.


Pain: Mild discomfort

Back to work: 1 day - possible bruising 

Results: after 4 weeks

Duration of results: 6-9 months

Procedure time: 20-30 minutes

Cost of Treatment: from £375


Why not book a consultation appointment with our head clinician Andrew?

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